Key Publications


Lee W, Frederick RO, Tonelli M, and Palmenberg AC
Solution NMR Determination of the CDHR3 Rhinovirus-C Binding Domain, EC1
Viruses, 13(2):159. PMID: 33499226 DOI: 10.3390/v13020159 [PDF]

Palmenberg AC, Kalejta RF
An Update on Gender Parity Trends for Invited Speakers at Four Prominent Virology Conference Series
J. Virology, 95(11):e00224-21. PMID: 33762415 DOI: 10.1128/JVI.00224-21. [PDF]


Sun Y, Watters K, Hill MG, Fang Q, Liu Y, Kuhn RJ, Klose T, Rossmann MG, and Palmenberg AC
Cryo-EM Structure of Rhinovirus C15a Bound to its Cadherin-related Protein 3 Receptor
PNAS, 117:6784-6791. PMID: 32152109 DOI: 10.1073/pnas.1921640117 [PDF] [PDF Support] PDB: 6PPO (C15a+EC1); 6PSF (C15a+EC1+2)

O’Neill MB, Lavel G, Teixeira JC, Palmenberg AC, and Pepperell CS
Genetic Susceptibility to Severe Childhood Asthma and Rhinovirus-C Maintained by Balancing Selection in Humans for 150,000 years
Human Mol Genetics, 29:736-744. PMID: 31841129 DOI: 10.1093/hmg/ddz304 [PDF]


Palmenberg AC
The Omics of Rhinoviruses
From: Enteroviruses: Omics, Molecular Biology, and Control (Edited by: William T. Jackson and Carolyn B. Coyne). Caister Academic Press, U.K. (2018) Pages: 51-67. DOI: org/10.21775/9781910190739.04 [PDF]

Watters K and Palmenberg AC
CDHR3 Extracellular Domains EC1-3 Mediate Rhinovirus C Interaction with Cells and as Recombinant Derivatives, are Inhibitory to Virus Infection
PlosPathogens., 14:e1007477. PMID: 30532249 DOI: 10.1371/journal.ppat.1007477 [PDF]


Watters K, Inakur B, Gardiner JC, Warrick J, Sherer NM, Yin J, and Palmenberg AC
Differential Disruption of Nucleocytoplasmic Trafficking Pathways by Rhinovirus 2A Proteases
J. Virology, 91:e02472-16. PMID: 28179529 DOI: 10.1128/JVI.02472-16 [PDF]

Palmenberg AC
Rhinovirus C, Asthma, and Cell Surface Expression of Virus Receptor CDHR3
J. Virology, 91:e0072-17. PMID: 28100615 DOI: 10.1128/JVI.00072-17 [PDF]

Kalejta RF, Palmenberg AC
Gender Parity for Invited Speakers at Four Prominent Virology Conference Series
J. Virology, 91(16) DOI: 10.1128/JVI.00739-17 [PDF]


Palmenberg AC
The Language of Life
Annu. Rev. Virol., 3:1-28. PMID: 27741404 DOI: 10.1146/annurev-virology-110615-035544 [PDF]

Bochkov YA, Watters K, Basnet S, Sijapati S, Hill M, Palmenberg AC and Gern JE
Mutations in VP1 and 3A Proteins Improve Binding and Replication of Rhinovirus C15 in HeLa-E8 Cells
Virology, 499:350-360. PMID: 27743961 DOI: 10.1016/j.virol.2016.09.025 [PDF]

Liu Y, Hill MG, Klose T, Chen Z, Watters K, Bochkov TA, Jiang W, Palmenberg AC, and Rossmann MG
Atomic Structure of a Rhinovirus C, a Virus Species Linked to Severe Childhood Asthma
PNAS, 113:8997-9002. PMID: 27511920 DOI: 10.1073/pnas.1606595113 [PDF] PDB: 5K0U (full); 5JZG (empty)


Bochkov YA, Watters K, Ashraf S, Griggs TF, Devries MK, Jackson DJ, Palmenberg AC, and Gern JE
Cadherin-related Family Member 3, A Childhood Asthma Susceptibility Gene Product, Mediates Rhinovirus C Binding and Replication
PNAS, 112:5485-5490. PMID: 25848009 DOI: 10.1073/pnas.1421178112 [PDF]


Bacot-Davis, VR, Ciomperlik, JJ, Basta, HA, Cornilescu, CC, Palmenberg, AC
Solution Structures of Mengovirus Leader Protein, its Phosphorylated Derivatives, and in Complex with Nuclear Transport Regulatory Protein, RanGTPase
PNAS, 111:15792-15797. PMID: 25331866 DOI: 10.1073/pnas.1411098111 [PDF]

Lee W, Watters,KE,Troupis AT, Reinin NM, Suchy FP, Moyer K, Frederick RO, Tonelli M, Aceti DJ, Palmenberg AC, Markley JL
Solution Structure of the 2A Protease from a Common Cold Agent, Human Rhinovirus C2, strain W12
PLOS One, 9(6):e97198 10.1371/journal.pone.0097198 [PDF]

Liggett SB, Bochkov YA, Pappas T, Lemanske RF Jr, Gern JE, Sengamaly N, Zhao X, Su Q, Fraser CM, and Palmenberg AC
Genome sequences of Rhinovirus A isolates from Wisconsin pediatric respiratory studies
Genome Announcements, 2(2):e00200-14. PMID: 24675855 DOI: 10.1128/genomeA.00200-14 [PDF]

Liggett SB, Bochkov YA, Pappas T, Lemanske RF Jr, Gern JE, Sengamaly N, Zhao X, Su Q, Fraser CM, and Palmenberg AC
Genome sequences of Rhinovirus B isolates from Wisconsin Pediatric respiratory studies
Genome Announcements, 2(2):e00202-14. PMID: 24675857 DOI: 10.1128/genomeA.00202-14 [PDF]

Liggett SB, Bochkov YA, Pappas T, Lemanske RF Jr, Gern JE, Sengamaly N, Zhao X, Su Q, Fraser CM, and Palmenberg AC
Genome sequences of Rhinovirus C isolates from Wisconsin pediatric respiratory studies
Genome Announcements, 2(2):e00203-14. PMID: 24675858 DOI: 10.1128/genomeA.00203-14 [PDF]

Palmenberg AC and Gern JE
Classification and evolution of human rhinoviruses
Methods in Molecular Biology, 1221:1-10. PMID: 25261302 DOI: 10.1007/978-1-4939-1571-2_1 [PDF]


Bochkov YA, Palmenberg AC, Lee WM, Rathe JA, Amineva SP, Sun X, Pasic TR, Jarjour NN, Liggett SB, Gern JE.
Molecular modeling, organ culture and reverse genetics for a newly identified human rhinovirus C.
Nature Medicine, 17:627-632. PMID: 21483405 DOI: 10.1038/nm.2358 [PDF]


Palmenberg AC, Spiro D, Kuzmickas R, Wang S, Djiken A, Rathe JA, Fraser-Liggett CM, and Liggett SB
Sequencing and analysis of all known human rhinovirus genomes reveal structure and evolution
Science, 324:55-59. PMID: 19213880 DOI: 10.1126/science.1165557 [PDF] [PDF Support] [PDF Seq Table] [Alignments]

Porter FW, Palmenberg AC
Leader-Induced Phosphorylation of Nucleoporins Contributes to Nuclear Import Inhibition by Cardioviruses
J. Virology, 83:1941-1951. PMID: 19073724 DOI: 10.1128/JVI.01752-08 [PDF]


Cornilescu CC, Porter FW, Zhao Q, Palmenberg AC, Markley JL
NMR Structure of the Mengovirus Leader Protein Zinc-Finger Domain
FEBS J., 582:896-900 (PDB ID: 2BAI) PMID: 18291103 DOI: 10.1016/j.febslet.2008.02.023 [PDF]


Bochkov YA and Palmenberg AC
Translational Efficiency of EMCV IRES in Bicistronic Vectors is Dependent upon IRES Sequence and Gene Location
BioTechniques, 41:283-290. PMID: 16989088 DOI: 10.2144/000112243 [PDF]

Porter F, Bochkov Y, Weise C, Palmenberg AC
A Picornaviral Protein Interacts with Ran GTPase and Disrupts Nucleocytoplasmic Transport
PNAS, 103:12417-12422. PMID: 16888036 DOI: 10.1073/pnas.0605375103 [PDF]


Fata-Hartley CL, Palmenberg AC
Dipyridamole Reversibly Inhibits Mengovirus RNA Replication
J. Virology, 79:11062-11070. PMID: 16103157 DOI: 10.1128/JVI.79.17.11062-11070.2005 [PDF]


Palmenberg AC and Sgro J-Y
Alignments and Comparative Profiles of Picornavirus Genera
The Molecular Biology of Picornaviruses, Semler & Wimmer, Eds., 2002, ASM Press, Washington, DC. pp 149-155. [PDF]


Martin LR, Duke GM, Osorio JE Hall DJ, Palmenberg AC
Mutational Analysis of the Mengo Virus Poly(C) Tract and Surrounding Heteropolymeric Sequences
J. Virology, 70:2027-2031. PMID: 8627731 DOI: 10.1128/JVI.70.3.2027-2031.1996 [PDF]


Hahn H, Palmenberg AC
Encephalomyocarditis Viruses with Short Poly(C) Tracts are More Virulent than their Mengovirus Counterparts
J. Virology, 69:4399-4406. PMID: 7884926 DOI: 10.1128/JVI.69.4.2697-2699 [PDF]


Luo M, Vriend G, Kamer G, Minor I, Arnold E, Rossmann M, Boege U, Scraba D, Duke G, Palmenberg AC
The Atomic Structure of Mengo Virus at 3.0 Atomic Resolution
Science, 235:182-191. PMID: 3026048 DOI: 10.1126/science.3026048 [PDF]